Prof. Irini Doychinova, DSc

Head of the Department:
Prof. Irini Doychinova, DSc
 

Tel.: (+359-2)9236-506
E-mail:  idoytchinova@pharmfac.mu-sofia.bg

Brief historical outline :

The Department of Chemistry was established as a separate teaching and research unit at the Faculty of Pharmacy in the autumn of 1959. Until then the courses in inorganic chemistry, analytical chemistry and physicochemistry were offered by the corresponding chairs at the Faculty of Natural Science and Mathematics at the University of Sofia “St. Kliment Ohridski”. Since 2010 section of Organic Chemistry was created within the Department of Chemistry. Heads of the department since its establishment were Prof. Dimitar Trendafelov, Prof. Omortag Budevsky, D.Sc., Prof. Dimitria Mihailova, D.Sc.. Prof. Darwin Ivanov, Ph.D.

GENERAL AND INORGANIC CHEMISTRY :

Staff:

Lecturers:

Teaching staff:

Technical staff – 2

Subject and duration of Course:

Core Subjects:

• Inorganic chemistry - I and II semesters
  (lectures 45 h, practicum 75часа).

Laboratories:

• Chemical laboratories - 2.
• Research laboratory -1

Main fields of research:

• Synthesis and physicochemical characterization of metal-organic complex compounds with biological activity.

ANALYTICAL CHEMISTRY :

Staff:
Lecturers:

 Teaching staff:

Technical staff – 2

Subject and duration of Course:

Core Subjects:

• Analytical Chemistry III-IV semesters
  (lectures – 60 h; practicum – 120 h).

Course offеred at:

• Drug analysis in biological media (in collaboration with Department of Pharmaceutical Chemistry), a modul of Clinical Pharmacy specialization -VI semester
  (lectures 45 h, practicum 75часа). The course is offered at undergraduate level and at postgraduate level.

Laboratories: 2.

Main fields of research:

• Quality control and standardization of drugs and drug forms;

Basic Laboratory Equipment:
Liquid chromatographers SHIMADZU, PERKIN-ELMER; spectrophotometers UV-VIS HEWLETT-PACKARD, SHIMADZU; densitometer CAMAG; potentiometer ORION; pH-meters METROHM; computers and periphery.

Organic chemistry :

History:

• 1942 The lectures of Organic Chemistry were delivered by Acad. Dimitar Ivanov, University of Sofia (Reaction of Ivanov);
• 1954 г. Section of Organic Chemistry was found within the Department of Pharmaceutical and Organic Chemistry.
• 1982 г. Independent Department of Organic Chemistry was established by Prof. Dr. Damian Danchev.
• 1986 г. Section of Organic Chemistry within the Department of Pharmaceutical Chemistry (head of Department: Prof. Dr. Jordan Gagauzov);
• 1990 г. The independence of the Department was restored under the guidance of Prof. Dr. Ivo Ivanov.

Staff:
Lecturers:

 Нехабилитирани преподаватели:

Technical staff – 2

Subject and duration of Course:

Core Subjects:

• Organic chemistry - III-IV semester
  (lectures - 60 h, practicum - 120 h).

Laboratories: 2.

Main fields of research:

• Synthesis of heterocyclic compounds and derivatives with potential biological activity.
• Asymmetric organic synthesis
• Development of novel anti-tuberculosis agent

Physical chemistry :

Stuff:
Lecturers:

 Assistant professors:

Technical staff – 2

Subject and duration of Course:

Core Subjects:

• Physical Chemisstry - IV-V semester
  (lectures - 45 h, practicum - 45 h).
• Pharmacokinetics - IX semester
  (lectures - 14 h, practicum - 42 h).

Facultative subject:

• Drug design - IX semester
  (lectures - 30 h, practicum - 30 h).

Laboratories: 2

Main fields of research: - Drug design :

• Quantity structure activity relationship (QSAR);
• Immuneinformatics
• Molecular docking
• Molecular dynamics